Effect of Atropine Sulfate Ointments and Gels on the Intraocular Pressure of Rabbit’s Eye

chemicaI stability of thiamine hydrochloride and wfwncrate in tablets prepared by direct granulation Its vising Span 40, stearic acid or PEG 6000 as gran-agents were studied in comparison with those pre-ifret granulation technique. Batches of tablets id good physical and mechanical properties were for this study. The stability testing was carried 5 and 95% relative humidity at two temperature and 45°C. The results obtained revealed that, iOf degradation of either thiamine hydrochloride us fumarate was increased as the relative humidity erature were increased. In case of thiamine hydro-i tablets, the highest stability data were obtained bleis prepared with stearic acid followed by those ttith PEG 3000. In case of ferrous fumarate the lability data were obtained from tablets prepared fic acid or Span 40. The degradation pathway of KS uas found to follow the first order kinetics